Antibacterial properties of Mangifera indica flower extracts on uropathogenic Escherichia coli.
Poongothai P., Rajan S.
Author Affiliation: Research and Development Center, Bharathiyar University, Coimbatore, India.
International Journal of Current Microbiology and Applied Sciences 2 : 104-111
Abstract : Uropathogenic Escherichia coli are the major cause of urinary tract infection. Modern combined antibiotics are used for the treatment of UTI, which cause various side effects and creates resistance among bacterial pathogens. To overcome these problems peoples turned towards indigenous medicinal system like siddha. Medicinal plants are the backbone of these indigenous system of medicine. Mangifera indica is commonly called as Mango. Traditionally dried mango flowers are astringent and given for diarrhoea, chronic dysentery, catarrah of the bladder. Antibacterial activity and qualitative phytochemical screening were done for aqueous and methanolic extracts by making use of standard methods. Antibacterial activity of Mangifera indica flower extracts were determined using disk diffusion, agar dilution methods. The results showed that the flower extracts of M. indica have antimicrobial activity against Uropathogenic E. coli. Methanol extracts showed the highest inhibition zone diameter of 22.6±1.2 mm. The plant extracts were shown to have a MIC 180±050 µg/ml for aqueous extract and 055±025 µg/ml for methanolic extract. Phytochemical screening of the extracts revealed the presence of phenolic compounds, flavonoids and tannins in both the extracts tested, which are known to inhibit bacterial growth by different mechanisms from those of synthetic drugs. These phyto-constituents may be responsible for the M. indica antibacterial activity.