Characterization of cross-reacting allergens in mango fruit.
Paschke A., Kinder H., Zunker K., Wigotzki M., Steinhart H., Wessbecher R., Vieluf I.
Author Affiliation: Institute of Biochemistry and Food Chemistry, University of Hamburg, Grindelallee 117, D-20146 Hamburg, Germany.
Allergy (Copenhagen) 56 : 237-242
Abstract : Allergic reactions to mango fruit have become increasingly important. A cross-reaction between mango fruit, various other foods, and respiratory allergens has been assumed but not investigated until now. The sera of nine patients were used to characterize cross-reacting allergens in mango fruits by EAST inhibition and immunoblot inhibition. EAST inhibition and immunoblot inhibition demonstrated that cross-reactions between mango fruits, mugwort pollen, birch pollen, celery, and carrot are based on allergens related to Bet v 1 and Art v 1, the major allergens of birch and mugwort pollen, respectively.