Spray drying of aqueous extract of Mangifera indica L (Vimang): scale up for the process.
Acosta-Esquijarosa J., Jáuregui-Haza U., Amaro-González D., Sordo-Martínez L.
Author Affiliation: Departamento de Desarrollo Tecnológico, Centro de Química Farmacéutica, Ave, 200 y 21, Apdo, 11600, Playa, Ciudad Habana, Cuba.
World Applied Sciences Journal 6 : 408-412
Abstract : Vimang is the brand name of an aqueous extract of Mangifera indica L (mango) and is widely used as antioxidant, analgesic and antinflamatory agent. It is obtained from mango's stem bark by decoction with water and further spray drying process. The aim of this study was to optimize the operation conditions of spray drying of Vimang to maximize recovery yield, minimizing cost and keeping the quality parameters of Vimang powder. Experimental 2 3 central composite factorial designs was used to investigate the influence of three parameters on the particle size, the moisture content, recovery yield and dimensional cost of spray-dried product. The obtained experimental results adequately fit to empirical quadratic models. Then, the optimal operating conditions were estimated from the empirical model and further experimentally verified. The process was successfully scale-up from laboratory equipment to industrial scale keeping the same optimal operating parameters.